I just tried it and used to take it twice a day, once in the morning and once at night. It helps a little for my "bone" pain in my bad leg, but what helped even more was the salve. I had a problem for over a month with such bad pain, soreness in the bone (not joint) and swelling. Rubbed a little on and within a few days, I could move the knee as if there was no problem and no more pain or swelling. The salve is expensive, though, but does last a long time.